C10 - Sunday, April 29, 1984 - North Shore News Looking for cancer From Hawaii Miracle Whip Salad Dressing 1 utre jar WOODWARD) 5 SUPREME BLEND Instant Coffee 10 oz. jar 4.57 WOOL WARS, Coffee Aid 500 g jar 2.17 rood Tht LAUINDEY Sunlight Detergent 4.8 xg vox 797 ches Mahala aan guitag apg tiki Ghana Nr on Tae Bae . Fresh Dole Pineapp le “ASSORTED # LAVOURS Woodward’s Ice Cream 227 2 tre carton NEM SON S CAL 369 g pkg laboratories all cancer continues. if ie NEB HAWAIIAN §] Papayas WA =PHILIPPINE Mangoes i mH A Iced Tea Mix 750 g tin 2°! MAXWELL b4Oobdoot Coffee Hlescuiilaar oe bona Back in 1961, enough tissue for was a constant consuming problem and Dr. IF ORINIA 287 THE WOMAN undergoing radium treatment for maintained and grown for cancer of the cervix hardly noticed as the young 4¢ecades. She succeeded - so researcher removed some cells from the area being well that she still hears today implanted with the radium.. from doctors in other coun- tries who are working with the descendants of those first The cancer was very ad- Nelly Auersperg was quick to — cells. vanced and the patient sur- vived for only six months, but more than 20 years later, her cells flive realize the value of cells that Working out of the could be kept in the Department of Anatomy at laboratory for use as and the University of B.C., Dr. in when needed. Auersperg’s chief area of in- the She applied for and obtain- terest in 1984 is cancer cell world where the fight against ed from the National Cancer biology - the study of cancer Institute of Canada (NCIC) cells themselves and their finding funding to develop a method _ relationship to normal cells. research by which cells that continued time- to resemble the cancer from blems in the control of “One of the biggest pro- which they came could be cancer,’’ she explains, ‘‘is Taste that Tropical Fruit 2°%., 95SE 57! /kg 2° ECUADOR | Bananas, ey 08.39%. ASSORTED CREAMS Peek Freans Biscuits 400 g pig. 197 HACOSS TR SoS Potato Chips krinkles Regular ¢ 200 g pkg. 97 Pepsi Cola bab Cal dd ABY O>Ra (Oth T 58° 750 mi bottle Pry. Lob peo cot berg ays boreres Libby’s Beans on Watt: Pork in Motasses 14 f. oz tin 67° that cancer cells are very similar to normal cells and it’s hard to treat one without affecting the other. We’re always tooking for dif- ferences between them that can be exploited. ‘‘Cancer cells vary, even among themselves. Within one organ — even within one tumor — cells vary in their growth requirements and growth rate. A tumor will change even with time, mak- ing it harder to treat.”” Dr. Auersperg’s efforts to determine the basis, at the cellular level, for the diversity among cancer cells involve two separate areas of study. One uses human cells; the other uses rat cells. **We take human cells ob- tained from tumor biopsies and grow them in culture — that is, in an environment that 1s greatly simplified in comparison to the body in which they first formed. The growth pattern varies. The cells in a cervical tumor, for example, may be clumped together or they may be spread out, We want to know if that growth pattern is dif- ferent when the cells are Side Spareribs 4”, FRESH Trout 8 oz FRESH each 1.99 Sole Fillets 7.47 x3 3-39 w. SUN RAY FROZEN Orange Juice 12% f. oz tin 99°° Kimberly DEL SEY Bathroom Tissue 157 4ronls Kitt NEX Facial Tissue 200 per pkg. KLEENEX WHIT 98° Dinner Napkins 30 per pkg. 1.07 grown outside the body and, if so, why? “‘A study we’ve just com- pleted indicates that proper- ties Of the cell surface may account for changes that do take place. If this is so, perhaps we can alter the sur- face structure of the cell and treat the tumor.”’ In another area of Dr. Auersperg’s lab, normal cells taken from rats are infected with a cancer virus. Examina- uon shows that the virus is taken up by the cells within hours. The cells become malignant anywhere from WOODWARD'S FROZEN ~ Whole Roasters 326 One to eight weeks later. Dr. Auersperg is par- ticularly interested in gene regulation. ‘‘We know that cancer cells in the body are all different from one another, but we don’t know to what extent this is determined by characteristics of the cells themselves and to what ex- tent it’s determined by the cell’s environment.”’ An example of gene regulation was contained in a Paper published by Dr. Auersperg in 1981, which described a study of ovarian cells. ‘*We discovered we Ie Soft Margarine 2 lb. tub WOODWARD 'S DANISH 1.37 Samsoe Cheese or Cream Havart Random cuts per kg Hl ORE WHITE por lb. 37! lark Sale Serviettes 120 per pkg. Ki bE NE X BOUTIOUL Facial Tissue 100 per pkg. NEW tte EDOM 95° Mini Pads Regular or Deodorant 30 po: pry 3.97 Gea ulmeba aaa ae EEN aa AE REE BOT Re Cll - Sunday, April 29, 1984 - North Shore News could infect certain cells with a certain virus, but it took the addition of a hormone to make the cell become malig- nant. The cells did not ac- quire the characteristics of malignant cells unless the hormone was added."’ Another aspect of Dr. Auersperg’s work involves growing cells from the ovary. Eighty per cent of ovarian cancers develop in the surface cells, which are extremely hard to isolate for study. Dr. Auersperg is very pro- ud that it was a former stu- dent of hers who developed a method for growing rat ovary surface epithelium. Growing human ovary surface epithelium with which to work is. difficult. With the help of funding from the National Cancer In- stitute of Canada, Dr. Auersperg is developing a method to grow the cells which give rise tO most ovarian cancers. This will provide the scientific com- munity with the first ex- perimental model to in- vestigate causes of ovarian cancer. For info call 879-5736. FRESH CANADIAN Leg of Lamb Whole or Butt Portion 8®° kg 372 FRESH ~ Oysters FRESH TEMPURA 8 0.2.39 Fish Cakes 8.80... 3.99 w. SUN RAY Strawberry Jam 750 mi tin 227 WOODWARD S OWN Bread WHITE Ob WHOLE Whe ATI 450 yg 85‘ Personal Shopping April 30 to May 5 We reserve the right to limit quantities Boric, ectfere trye at bcrwee Miurcrtbaccd acid C hererttotcnk cs teorer RAE EPPA DGB AMES GAL Sar tam badd a thal WAR TD